deRMA Skin Institute
33 Farley Drive Unit #8
Guelph, ON N1L0B7
Phone: (888) 803-3762
Monday–Friday: 9 a.m.–4:30 p.m.
5 Dimension Skin Plan™
Facial aging occurs in multiple ways that involve much more than just the skin’s appearance. Changes to fat, muscles, and bones underneath the skin also influence your overall appearance, and these changes are unique to each individual. Our signature approach to anti-aging treatment in Guelph, ON, is the 5-Dimension Skin Plan™, an innovative, science-based approach developed by Royal College-certified dermatologist Dr. Dusan Sajic using the latest research, medicine, and technology.
The 5 Dimension Skin Plan is offered exclusively at deRMA Skin Institute and sets our practice apart from other skincare specialists. By addressing the integrated causes of aging—whether you’re in your 20s or 70s or anywhere in between—we can delay or reverse signs of aging so that you look like the healthiest, most vibrant version of yourself.
Learn more about how we can prevent and reverse aging in your age group.
What Causes an Aged Appearance?
Why do wrinkles develop? What causes age spots to appear? Why does skin sag as we get older? How can we retain a youthful face shape? Instead of simply addressing the symptoms of aging, such as wrinkled skin, Dr. Sajic and the other specialists at our practice use the 5 Dimension Skin Plan to create comprehensive treatment plans starting with the foundation.
Understanding the 5 dimensions of facial aging and the condition of each patient enables us to tailor our treatments for a patient’s specific needs.
The 5 dimensions of aging include:
Bone Loss
Few people consider bones an important part of facial aging. But after about age 35, the regeneration of bone cells decreases, which can lead to under-eye hollows, flattened cheeks, an undefined jawline, and a receding chin. Additionally, the loss of structure beneath the skin can cause sagging, lines, and folds.
Fat Loss or Displacement
Fat diminishes and shifts downward as we age, so features that had youthful plumpness with smooth skin begin sagging. The result can be jowls, a double chin, and bags under the eyes called festoons and malar mounds.
Structural Skin Loss
This is the dimension that’s most commonly addressed by aesthetic treatments such as laser skin rejuvenation, microneedling, and other procedures that stimulate the production of new collagen. As we age, the skin produces less elastin, collagen, and hyaluronic acid—all of which are the essential building blocks of tight, smooth skin.
Textural and Pigment Changes to the Skin’s Surface
Age-related changes to the skin’s texture are caused primarily by sun exposure, resulting in brown spots and other discolouration. Other textural changes noticed with age include scarring, roughness, and wrinkles.
Muscle and Movement Imbalances
Expression lines, also called dynamic wrinkles, develop after years of squinting, smiling, frowning, and all the other ways we change expressions. These all involve the movement of tiny facial muscles that result in crow’s feet, the “11s,” forehead wrinkles, and marionette lines around the mouth.

Interested In This Treatment?
Request A ConsultationDr. Sajic developed deRMA Skin Institute to provide medical and cosmetic dermatology patients access to state-of-the-art technology and treatments. As a Fellow of the Royal College of Physicians and Surgeons of Canada and the American Academy of Dermatology, Dr. Sajic’s accomplishments as a researcher, educator, and dermatology innovator have made him one of Ontario’s leading dermatologists.
Meet Dr. SajicCredentials you can trust


5 Dimension Skin Plan Treatments by Age
As we age, multiple changes occur—both visible and invisible—that we at deRMA Skin Institute address with customized treatment plans. Unlike many other practices that focus only on a single concern, Dr. Sajic and our team of specialists design treatments only after assessing all 5 dimensions of facial aging and skin health.
That doesn’t mean every patient needs a specific treatment for each dimension—patients in their 20s may only require a bit of “preventative BOTOX®, for example. It’s important, however, that we assess each patient’s needs from a comprehensive viewpoint.
With that in mind, here’s a look at typical treatments we recommend for patients at varying stages of life:
Ages 25-35
You may have heard the phrase “prejuvenation” as you researched anti-aging treatments online. This is the age group where preventative measures can truly postpone the onset of wrinkles and other signs of aging. In addition to using a broad-spectrum sunscreen, retinol, and vitamin C as part of your skincare regimen, micro-injections of BOTOX (sometimes called “Baby BOTOX”) can help prevent the development of crow’s feet, worry lines, and other “dynamic” wrinkles caused by muscle movements.
Skin at this age still retains ample amounts of collagen and elastin to prevent sagging, and bone loss and fat loss aren’t really a concern, either. “Starter” laser treatments, such as ClearLift™, are gentle, no-downtime procedures that work well with BELA MD facials to keep your skin glowing and refreshed.
Ages 35-45
At this age, all 5 dimensions of facial aging typically need to be addressed to maintain a youthful appearance. Various dermal fillers, including Sculptra® and Radiesse®, effectively offset bone loss and fat loss, while microneedling combined with radiofrequency energy stimulates the production of new collagen and elastin to restore firmness to your skin. We recommend targeting more pronounced frown lines and other expression lines with BOTOX, Dysport®, or XEOMIN® to relax the muscles responsible for these wrinkles.
Dr. Sajic is a leader in the research of leading-edge aesthetic lasers, and this is the age where we start to see more significant changes to the skin’s texture that can be addressed with a combination of less aggressive lasers such as DyeVL and ClearLift. Light to medium chemical peels are another skin resurfacing option at this age.
Ages 45-55
Combining more aggressive laser skin resurfacing with cosmetic injectables such as fillers and BOTOX addresses textural changes caused by the steep drop in collagen and elastin production and the increasing loss of bone and fat. We may recommend ablative fractional laser resurfacing at this point, such as CO2 or Pixel® Erbium lasers, which involve some downtime. Patients concerned about jowls, nasolabial folds, and lax neck skin can benefit from AccuTite, a non-invasive alternative to facelift surgery, combined with RF microneedling, and diluted Radiesse®.
Ages 55 and Above
Many of the same treatment combinations used for patients between ages 45 and 55 are appropriate even as you get older. The difference now is that facial plastic surgery may be the best approach to accomplish your rejuvenation goals. If you do get a facelift, eyelid surgery, or some other surgical procedure, nonsurgical treatments can help maintain the results.
Schedule a Consultation
Consulting with Dr. Sajic or another board-certified dermatologist or plastic surgeon is an essential step of the 5 Dimension Skin Plan. Patients looking for a comprehensive approach to anti-aging treatments in Kitchener, Cambridge, and surrounding areas in Southwestern Ontario choose deRMA Skin Institute for their treatments. Request a consultation using the online form or call us at (888) 803-3762 to schedule an appointment.